Mechanism and theory in organic chemistry (Lowry, Thomas H.; Richardson, Kathleen Schueller)

Two metrics in a graph theory modeling of organic chemistry

Balai, V., V. KvasniEka and J. Pospichal, Two metrics in a graph theory modeling of organic chemistry, Discrete Applied Mathematics 35 (1992) 1-19. Two different metrics in the graph theory model of organic chemistry are defined. The chemical distance between two graphs (molecules) taken from the same family of isomeric graphs S, (where p is a number of vertices and q is a number of edges and l...

Molecular Mechanism of Acrylamide Neurotoxicity: Lessons Learned from Organic Chemistry

BACKGROUND Acrylamide (ACR) produces cumulative neurotoxicity in exposed humans and laboratory animals through a direct inhibitory effect on presynaptic function. OBJECTIVES In this review, we delineate how knowledge of chemistry provided an unprecedented understanding of the ACR neurotoxic mechanism. We also show how application of the hard and soft, acids and bases (HSAB) theory led to the ...

Organic chemistry in water.

Water has emerged as a versatile solvent for organic chemistry in recent years. Water as a solvent is not only inexpensive and environmentally benign, but also gives completely new reactivity. The types of organic reactions in water are broad including pericyclic reactions, reactions of carbanion equivalent, reactions of carbocation equivalent, reactions of radicals and carbenes, transition-met...

Organic and Biomolecular Chemistry

Thomas Eisner: Interpreter extraordinaire of nature's chemistry.

O n March 25, 2011, Thomas Eisner died after a long and courageous battle with Parkinson’s disease. His tremendous legacy included founding and nurturing the scientific discipline of chemical ecology. Tom, though, might be the only person in the field to dispute his rights to the title, “Father of Chemical Ecology”—indeed, in one interview (1), he wryly opined that such claims cried out for DNA...